Term Memory and Restitution During Ventricular Fibrillation in Human Hearts : An In - vivo Study
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چکیده
Short Title: Farid et al, Memory and Restitution during human VF. n nad ad ad ad ad ad ada a a a a a a an an an an an an and d d d d d d Abstract Background: Action potential duration (APD) variation is an important determinant of wavebreak
منابع مشابه
Short-term memory and restitution during ventricular fibrillation in human hearts: an in vivo study.
BACKGROUND Action potential duration (APD) variation is an important determinant of wave break and reentry. The determinants of APD variability during early ventricular fibrillation (VF) in myopathic human hearts have not been studied. The objective of this study was to study the role of APD restitution and short-term cardiac memory on variation in human VF. METHODS AND RESULTS The study cons...
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Background—Action potential duration (APD) variation is an important determinant of wave break and reentry. The determinants of APD variability during early ventricular fibrillation (VF) in myopathic human hearts have not been studied. The objective of this study was to study the role of APD restitution and short-term cardiac memory on variation in human VF. Methods and Results—The study consis...
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BACKGROUND The combined effects of excitability and action potential duration (APD) restitution on wavefront dynamics remain unclear. METHODS AND RESULTS We used optical mapping techniques to study Langendorff-perfused rabbit hearts. In protocol IA (n=10), D600 at increasing concentrations was infused during ventricular fibrillation (VF). With concentration increased to 0.5 mg/L, fast VF (dom...
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BACKGROUND Restitution kinetics and alternans of ventricular action potential duration (APD) have been shown to be important determinants of cardiac electrical stability. In this study, we tested the hypothesis that APD restitution and alternans properties differ between normal and diseased human ventricular myocardium. METHODS AND RESULTS Monophasic action potentials were recorded from the r...
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